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Fetal Ductus Arteriosus Patency

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Dr Henry Jefferson, Consultant Anaesthetist

#QuestionFeedback 12. Fetal Ductus Arteriosus What keeps the ductus arteriosus patent during fetal life? Two important factors are: • LOW fetal oxygen tension • HIGH prostaglandin E₂ activity Following birth, increasing oxygen tension and decreasing prostaglandin concentrations promote ductal constriction. Feedback highlighted that the original answer simply stated 'prostaglandin E₂' without specifying a HIGH concentration.

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